rheumatoid arthritis (RA) is a specific type of arthritis that typically affects joints–hands, wrists, knees–but can also damage a wide variety of internal systems, such as your circulatory system. Rheumatoid arthritis initially affects the lining of joints and connective tissue (called the synovial membrane), causing swelling that, in the long-term, can result in bone erosion and joint damage.¹ RA is an autoimmune disease, meaning that the body’s natural immune system works against itself. Immunity is the body’s natural way of defending you from a foreign invader, like a virus, a bacteria, or an injury. When the immune system is persistently activated, it triggers chronic inflammation. For example, when you fall and hit your knee, it will swell (it’s inflamed). This swelling tells the knee that tissue has been damaged and repair is needed. Such chronic inflammation, if left unchecked, can lead to persistent and progressive joint damage as with RA. Once developed, rheumatoid arthritis typically becomes a chronic disease. Getting ahead of the condition early and treating it as soon as possible (such as after the first sign of swelling) is key to reducing lifelong pain. People who receive early treatment intervention have a better chance of improving their lives sooner, and are more likely to lead an active life, says the ACR. These individuals are also less likely to require joint replacement surgery due to excessive joint damage.
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